3D Spatial Transcriptomics at Scale
At Cubase Bio, we develop technologies to transform drug development and disease research by revealing the third dimension of spatial biology.
Flat biology misses the true biological picture
Traditional spatial methods force a compromise: sequencing provides depth but destroys tissue architecture via thin-slicing, while microscopy suffers from limited multiplexing and low throughput.
Cubase Bio eliminates this trade-off. Our technology delivers true 3D spatial transcriptomics combining high-throughput sequencing depth with intact 3D structural architecture.
A reagent-based workflow.
No optics required.
Discover 3D Spatial Insights:
Extract. Sequence and Reconstruct
Compatible with your existing hardware
Once barcoded, simply dissolve the sample to extract and sequence the library using any standard DNA sequencer on the market.
Generate a 3D reconstruction with our software
From the raw sequencing data, our proprietary software mathematically decodes the molecular networks, maps the proximity data, and reconstructs the 3D spatial location of every transcript within the original 3D tissue.
Built for scalable screening.
Goodbye, flat biology!
Whether you are validating therapeutic targets in thick tissues or screening drug compounds across hundreds of organoids or model organisms, CubaseBio brings high-throughput genomic scale to intact 3D structures.
